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Do you think about a patient who overdosed or someone who is experiencing a toxic side effect from a medication

10.1016/j.theriogenology.2020.09.012 38

Furthermore, the increased levels of tau phosphorylation were significantly reduced by the inhibition of GSK-3, CDK5, and calpain, indicating that tau kinases activated by calcium overload are directly involved in the increase of tau phosphorylation